Palestinian death toll rises as Israel opens fire on Gaza border protest
Those injured on Friday included protesters hit by live ammunition and rubber-coated steel bullets, while others were overcome by tear gas. It has not yet provided a breakdown.
The violence erupted as Palestinians began a planned series of demonstrations, starting with the commemoration of Land Day, and intended to continue into May.
Read more: Palestinians pledge to return home with non-violent marches
Tens of thousands of Gaza residents streamed to five tent camp sites, each located several hundred metres from the border wall. From there, large crowds marched to the heavily fortified fence, and some among them started throwing stones at Israeli soldiers who responded with live fire, tear gas and rubber bullets.
The Israeli military said thousands participated, and that troops opened fire at the "main instigators" of the stone-throwing - but the casualty list disputes that version of events.
Later on Friday Israel's army said it targeted three Hamas sites in Gaza with tank fire and an air strike after what it said was an attempted gun attack on soldiers by Palestinians along the border.
The alleged shooting attack caused no injuries, the statement said.
Read more: Palestinian Land Day resistance comes at critical time
The first Palestinian casualty was farmer Omar Wahid Samur, killed by Israeli shelling early on Friday.
Two men, Mohammed Abu Amar and Mohammed Abu Muammar, were also killed in separate violence, and 16-year-old Ahmed Ouda was shot dead.
Jihad Farina, 33, became the sixth person killed when he was shot east of Gaza City.
The march kicks off up to six weeks of protests dubbed "The Great March of Return", in the run-up to the inauguration of the new US embassy in Jerusalem around May 14.
A previously published version of this article, sourced from external agencies, contained terminology which was inconsistent with our in-house style guide.